Tuesday, 30 September 2008

Er, what's an adaptogen?

I couldn't help noticing the blurb in this advert in the back of a triathlon magazine I was recently perusing.

Sport Elagen

combining the adaptogenic effects of ES with the anti-oxidant and catalytic
properties of Co Q10

scientifically designed for sportsmen and sportswomen


Phew. I have to admit this is the kind of pseudo-scientific hogwash that really sets my bullshit detector clanging. The advert has a website at the bottom - http://www.elagen.com/

I thought I would start picking the bones out of this advert...

It turns out ES is Eleutherococcus Senticosus - a herb. Elagen capsules are "a highly concentrated pure root extract measured to the correct potency proven to provide maximum effect."

One of the first questions you might ask is what is an adaptogen? I have no recollection of the mention of adaptogens in any physiology lecture I have attended or any textbook I have ever read. Maybe I was snoozing in my lectures but luckily the website is on hand to inform me:


In the 1950's Prof Brekhman of the pharmacological department of the Far East Scientific Centre of the Russian academy of Sciences recognised the potential value of the root and initiated extensive research into its properties. He subsequently classified Eleutherococcus as an 'adaptogen'. An adaptogen is a natural plant substance, which acts to normalise the body's systems in harmony with the normal metabolic, biochemical and immunological processes, as such adaptogens are innocuous and cause no harm. Adaptogens should have a non-specific action, such is the ability of Eleutherococcus to modulate stress and improve performance under a wide variety of stressful conditions.
So adaptogens have a non-specific action that causes the body to work normally. Hmm, never mind the hundreds of thousands of years of evolution that has resulted in the mind-boggling sophistication and elegance of human homeostasis. An adaptogen can make homeostasis even better! It would, of course, be tremendously difficult to prove it wasn't working.

I wonder if this feeds into the psyche of some athletes when it comes to performance enhancing drugs. At one end of the spectrum is the sheer naked cheating of a blood doper. By some artificial means the oxygen carrying red blood cells are augmented. However, at the bottom end this can all get much more woolly. Does taking an adaptogen constitute cheating through performance enhancing substances? The answer is probably no; not unless placebos appear on the international list of proscribed drugs.

4 comments:

Elaine said...

It's all woo and for the gullible only, sadly.

Dr Aust said...

I'm one of those crusty physiologists who teach the Northern Doctors of the future, and I've never heard of an "adaptogen" either.

Although, thanks to the wonders of PubMed, I can tell you that there is a recent-ish small systematic review of Eleutherococcus (aka "Siberian Ginseng") in exercise, which doesn't seem to bear out the manufacturer's claims. Funny that.

And as for Coenzyme Q10... don't get me started.

Northern Doctor said...

Thank you Dr Aust. You just beat me to the punch as I was teeing up another post highlighting that very study. I am still chasing some of the other claims they make...
I am looking forward to sitting down later and enjoying your Co Q10 post.

Dr Aust said...

Sorry to have spoiled the punchline, ND.

It does seem to be rather a emblematic example of the "daft extrapolation" fallacy:

"It does something in cells in a dish, so of course...."

Talking of which, apparently a shedload of the stuff might make you live longer if you are a soil-dwelling Nematode worm.

So obviously good for triathletes, then.